Scoring Process

The judging panel’s evaluation of the submissions will be based on the following scoring criteria:

Factor 1. Product Quality Assessment (100 points)

Each team will receive one opportunity for on-site production of the sample designated for later analytical characterization. This process will be conducted with a Challenge judge present during the entire production period. The system must be started from a non-operating condition and produce the sample within 7 hours of starting the system. Pauses in system operations are permitted but after 7 continuous hours have elaspsed since initial system start, no additional product will be accepted.

The sample must be in the form of a liquid or solid for verification analysis. The team must provide the analytical methodology used to identify and quantify the target compounds. The quantity of sample produced for confirmatory analysis must be (at least) the same amount that was used by the team to identify and quantify conversion products to allow replication of the team’s results by an independent laboratory. The amount of sample required will be confirmed in consultation with judges prior to the on-site testing.

In addition to providing the sample, the team must indicate the predicted compound(s) in the sample, indicate if a racemic mixture of sugars is expected and approximate concentrations. The sample must contain one or more challenge target compounds listed in the Challenge Target Compound table. The sample will be collected by the judge, sealed in a provided container, and shipped to an independent laboratory for verification. Note, the sample will only be evaluated for up to five (5) target compounds identified by the team. Beyond these five compounds, any additional target compounds will not be considered in the judging. Any preliminary analysis during system development/assessment is the responsibility of the team.

Scoring The team’s product will be examined using an independent chemical analysis to determine if any of the targeted compounds the Challenge Target Compound table are present. If enantiomers of the targeted compounds are present, the mass of each will be measured. The total score will be calculated by taking the mass of the most desired enantiomer “D” form minus the mass of the undesired “L” form. For example, if equal amounts of “D” and “L” glucose are found, then no points will be given for that compound.

An additional 10 points will be added to a team’s score for providing a Mid-Point Progress Update. These points are optional and are not subtracted if an update is not provided. With these points, the maximum possible score for this challenge is 110.